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Semiconductor Chip Manufacturing: Related to Birth Defects, Cancer and Miscarriages The process of semiconductor chip fabrication in clean rooms involves exposure to photoresist containing glycol ethers and other dangerous solvents. There have been several cases litigated against National Semiconductor, IBM and Intel based on exposure leading to birth defects, miscarriages and infertility. Clean Room Workers May be Exposed during the Semiconductor Chip Manufacturing Process. Manufacturing a computer chip involves a complex fabrication process, using photolithography and photoresist and harmful solvents that can injury plant clean room workers and spin coaters who are exposed. Injuries Caused by Photoresist include: |